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Atomistic characterization of binding modes and affinity of peptide inhibitors to amyloid-
Fufeng LIU,Wenjie DU,Yan SUN,Jie ZHENG,Xiaoyan DONG
Frontiers of Chemical Science and Engineering 2014, Volume 8, Issue 4, Pages 433-444 doi: 10.1007/s11705-014-1454-6
Keywords: Alzheimer’s disease amyloid β-protein peptide inhibitors protein-protein interaction molecular
Cystine oligomers successfully attached to peptide cysteine-rich fibrils
Christian Bortolini,Mingdong Dong
Frontiers of Chemical Science and Engineering 2016, Volume 10, Issue 1, Pages 99-102 doi: 10.1007/s11705-016-1554-6
Keywords: cysteine peptide fibrils gold nanoparticles amyloids oligomers nanomaterials
Glucagon-like peptide-2 exhibits protective effect on hepatic ischemia-reperfusion injury in rats
Naci Topaloğlu,Adem Küçük,Şule Yıldırım,Mustafa Tekin,Havva Erdem,Mustafa Deniz
Frontiers of Medicine 2015, Volume 9, Issue 3, Pages 368-373 doi: 10.1007/s11684-015-0403-1
Glucagon-like peptide-2 (GLP-2) has potent anti-inflammatory effects and protects against experimental
Keywords: ischemia/reperfusion liver glucagon-like peptide-2 alanine aminotransferase
Ripen NSENGA MD, Longxian CHENG PhD, Mei’an HE PhD, Tangchun WU PhD,
Frontiers of Medicine 2009, Volume 3, Issue 4, Pages 437-442 doi: 10.1007/s11684-009-0074-x
Keywords: natriuretic peptide precursor A coronary heart disease gene polymorphism allelic discrimination polymorphism
Abbas TEIMOURI, Nasrin SOLTANI, Alireza Najafi CHERMAHINI
Frontiers of Chemical Science and Engineering 2011, Volume 5, Issue 1, Pages 43-50 doi: 10.1007/s11705-010-0532-7
Keywords: corrosion inhibitors mild steel acidic medium theoretical studies DFT
Mitogen-activated protein kinase pathway inhibitors: inhibitors for diseases?
Xu WANG MS, Xiao-Wei GONG MD, PhD, Yong JIANG MD, PhD, Yu-Hua LI PhD,
Frontiers of Medicine 2010, Volume 4, Issue 1, Pages 46-53 doi: 10.1007/s11684-010-0010-0
Keywords: mitogen-activated protein kinase drug target inhibitor signal transduction disease
Zhen Xiang, Yingyan Yu
Frontiers of Medicine 2019, Volume 13, Issue 1, Pages 24-31 doi: 10.1007/s11684-019-0679-7
Keywords: immune checkpoint blockade sensitivity resistance data mining
Analysis of interactions of immune checkpoint inhibitors with antibiotics in cancer therapy
Frontiers of Medicine 2022, Volume 16, Issue 3, Pages 307-321 doi: 10.1007/s11684-022-0927-0
Keywords: tumor immunotherapy immune checkpoint inhibitor antibiotics gut microbiota drug–drug interaction
Advances in newly developing therapy for chronic hepatitis C virus infection
Paul J. Pockros
Frontiers of Medicine 2014, Volume 8, Issue 2, Pages 166-174 doi: 10.1007/s11684-014-0334-2
Chronic hepatitis C virus (HCV) infection afflicts a reported 170 million people worldwide and is often complicated by cirrhosis and hepatocellular carcinoma. Morbidity and mortality are decreased with the successful treatment of chronic HCV infection. Increased understanding of the HCV has allowed further development of new direct-acting antiviral (DAA) agents against the HCV and has also allowed the development of IFN-free oral treatment regimens. In late 2013 the first nucleotide polymerase inhibitor regimen with RBV alone for genotypes 2/3 and in combination with a 12-week regimen of PEG-IFN+RBV for genotypes 1, 4 was approved for use in the US. A number of promising new DAA regimens which are IFN-free are in phase 3 development and the first will likely be approved for use in the US in 2014. The currently approved regimens are discussed in detail and currently available data on future regimens are reviewed herein.
Keywords: direct-acting antiviral (DAA) nucleotide polymerase inhibitors protease inhibitors
Frontiers of Agricultural Science and Engineering 2022, Volume 9, Issue 1, Pages 133-145 doi: 10.15302/J-FASE-2021401
Keywords: herbicide / HPPD / inhibitor / quinoxaline / triketon
Huining HE, Junxiao YE, Jianyong SHENG, Jianxin WANG, Yongzhuo HUANG, Guanyi CHEN, Jingkang WANG, Victor C YANG
Frontiers of Chemical Science and Engineering 2013, Volume 7, Issue 1, Pages 9-19 doi: 10.1007/s11705-013-1306-9
Keywords: insulin cell penetrating peptide mucoadhesive composites oral delivery
Monitoring checkpoint inhibitors: predictive biomarkers in immunotherapy
Min Zhang, Jingwen Yang, Wenjing Hua, Zhong Li, Zenghui Xu, Qijun Qian
Frontiers of Medicine 2019, Volume 13, Issue 1, Pages 32-44 doi: 10.1007/s11684-018-0678-0
Keywords: immune checkpoint companion diagnosis PD-L1 tumor mutation burden immune score
Xiaohuan Wang, Peng Zou, Fan Wu, Lu Lu, Shibo Jiang
Frontiers of Medicine 2017, Volume 11, Issue 4, Pages 449-461 doi: 10.1007/s11684-017-0589-5
Keywords: emerging and re-emerging viruses small-molecule inhibitor coronavirus Ebola virus Zika virus life cycle
Rational Design of and Mechanism Insight into an Efficient Antifreeze Peptide for Cryopreservation
Haishan Qi,Yihang Gao,Lin Zhang,Zhongxin Cui,Xiaojie Sui,Jianfan Ma,Jing Yang,Zhiquan Shu,Lei Zhang,
Engineering doi: 10.1016/j.eng.2023.01.015
Keywords: Antifreeze peptides Evolution analysis Ice recrystallization inhibition Molecular dynamics simulation Cryopreservation Synthetic biology
Multi-Peptide Adsorption on Uncharged Solid Surfaces: A Coarse-Grained Simulation Study Research
Ruosang Qiu, Jie Xiao, Xiao Dong Chen
Engineering 2020, Volume 6, Issue 2, Pages 185-194 doi: 10.1016/j.eng.2018.12.012
Keywords: Peptide chains Aggregates Adsorption Coarse-grained simulation
Title Author Date Type Operation
Atomistic characterization of binding modes and affinity of peptide inhibitors to amyloid-
Fufeng LIU,Wenjie DU,Yan SUN,Jie ZHENG,Xiaoyan DONG
Journal Article
Cystine oligomers successfully attached to peptide cysteine-rich fibrils
Christian Bortolini,Mingdong Dong
Journal Article
Glucagon-like peptide-2 exhibits protective effect on hepatic ischemia-reperfusion injury in rats
Naci Topaloğlu,Adem Küçük,Şule Yıldırım,Mustafa Tekin,Havva Erdem,Mustafa Deniz
Journal Article
The role of natriuretic peptide precursor A gene polymorphism in the development of coronary heart disease
Ripen NSENGA MD, Longxian CHENG PhD, Mei’an HE PhD, Tangchun WU PhD,
Journal Article
Synthesis of mono and bis-4-methylpiperidiniummethyl-urea as corrosion inhibitors for steel in acidic
Abbas TEIMOURI, Nasrin SOLTANI, Alireza Najafi CHERMAHINI
Journal Article
Mitogen-activated protein kinase pathway inhibitors: inhibitors for diseases?
Xu WANG MS, Xiao-Wei GONG MD, PhD, Yong JIANG MD, PhD, Yu-Hua LI PhD,
Journal Article
Screening responsive or resistant biomarkers of immune checkpoint inhibitors based on online databases
Zhen Xiang, Yingyan Yu
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Analysis of interactions of immune checkpoint inhibitors with antibiotics in cancer therapy
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Advances in newly developing therapy for chronic hepatitis C virus infection
Paul J. Pockros
Journal Article
DISCOVERY OF TRIKETONE-QUINOXALINE HYBRIDS AS POTENT HPPD INHIBITORS USING STRUCTURE-BASED DRUG DESIGN
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Overcoming oral insulin delivery barriers: application of cell penetrating peptide and silica-based nanoporous
Huining HE, Junxiao YE, Jianyong SHENG, Jianxin WANG, Yongzhuo HUANG, Guanyi CHEN, Jingkang WANG, Victor C YANG
Journal Article
Monitoring checkpoint inhibitors: predictive biomarkers in immunotherapy
Min Zhang, Jingwen Yang, Wenjing Hua, Zhong Li, Zenghui Xu, Qijun Qian
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Development of small-molecule viral inhibitors targeting various stages of the life cycle of emerging
Xiaohuan Wang, Peng Zou, Fan Wu, Lu Lu, Shibo Jiang
Journal Article
Rational Design of and Mechanism Insight into an Efficient Antifreeze Peptide for Cryopreservation
Haishan Qi,Yihang Gao,Lin Zhang,Zhongxin Cui,Xiaojie Sui,Jianfan Ma,Jing Yang,Zhiquan Shu,Lei Zhang,
Journal Article